Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation
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DOI: 10.1016/j.redox.2017.04.035
Abstract: To study the physiological roles of NADH and NADPH homeostasis in cancer, we studied the effect of NNT knockdown on physiology of SK-Hep1 cells. NNT knockdown cells show limited abilities to maintain NAD+ and NADPH… read more here.
Keywords: nnt deficiency; transhydrogenase nnt; proliferation; deficiency dysregulates ... See more keywords