Clinical features of 35 Down syndrome patients with transient abnormal myelopoiesis at a single institution
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DOI: 10.1007/s12185-020-03066-7
Abstract: Transient abnormal myelopoiesis (TAM) is a unique clonal myeloproliferation characterized by immature megakaryoblasts that occurs in 5–10% of neonates with Down syndrome (DS). Although TAM regresses spontaneously in most patients, approximately 20% of TAM cases… read more here.
Keywords: lbp tam; abnormal myelopoiesis; blast percentage; tam ... See more keywords
Bullous eruptions in transient abnormal myelopoiesis with normal phenotype
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DOI: 10.1136/bcr-2022-251523
Abstract: Cutaneous lesions are common manifestation of congenital leukaemia especially myeloid type with incidence of 25%–50% in reported cases. It is relatively rare in transient abnormal myelopoiesis (TAM) seen in trisomy 21 (~10%). The rashes seen… read more here.
Keywords: myelopoiesis normal; transient abnormal; abnormal myelopoiesis; bullous eruptions ... See more keywords
Rapid next-generation sequencing aids in diagnosis of transient abnormal myelopoiesis in a phenotypically normal newborn
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006865
Abstract: Transient abnormal myelopoiesis (TAM) is a myeloid proliferative condition with leukemic potential, almost exclusively seen in infants with trisomy 21 (Down syndrome [DS]). We report here an unusual case of a neonate without DS who… read more here.
Keywords: abnormal myelopoiesis; diagnosis; transient abnormal; phenotypically normal ... See more keywords