Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cell"
DOI: 10.1016/j.molcel.2021.01.039
Abstract: Summary Despite their diverse biochemical characteristics and functions, all DNA-binding proteins share the ability to accurately locate their target sites among the vast excess of non-target DNA. Toward identifying universal mechanisms of the target search,… read more here.
Keywords: binding proteins; dna; transient non; target search ... See more keywords
Probing transient non-native states in amyloid beta fiber elongation by NMR.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc01067j
Abstract: Using NMR to probe transient binding of Aβ1-40 monomers to fibers, we find partially bound conformations with the highest degree of interaction near F19-K28 and a lesser degree of interaction near the C-terminus (L34-G37). This… read more here.
Keywords: probing transient; transient non; states amyloid; transient ... See more keywords