THERAPY-INDUCED POLYPLOIDIZATION AND SENESCENCE; COINCIDENCE OR INTERCONNECTION?
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DOI: 10.1016/j.semcancer.2020.11.015
Abstract: Polyploid somatic cells have 'programmed' roles in normal development and stress responses. Transient polyploidy states have been observed in several tumor types at early stages of tumorigenesis. They can give rise to the aneuploidy state… read more here.
Keywords: senescence; transient polyploidy; cancer; induced polyploidization ... See more keywords