Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1101/2022.01.20.477063
Abstract: The expression of the pluripotency factors OCT4, SOX2, KLF4 and MYC (OSKM) can convert somatic differentiated cells into pluripotent stem cells in a process known as reprogramming. Notably, cycles of brief OSKM expression do not… read more here.
Keywords: oskm expression; multi omic; transient reprogramming; transient ... See more keywords
Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13578
Abstract: The expression of the pluripotency factors OCT4, SOX2, KLF4, and MYC (OSKM) can convert somatic differentiated cells into pluripotent stem cells in a process known as reprogramming. Notably, partial and reversible reprogramming does not change… read more here.
Keywords: transient reprogramming; transient; naturally aged; rejuvenation naturally ... See more keywords