Epithelial-to-mesenchymal transition in cancer: complexity and opportunities
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers of medicine"
DOI: 10.1007/s11684-018-0656-6
Abstract: The cell-biological program termed the epithelial-to-mesenchymal transition (EMT) plays an important role in both development and cancer progression. Depending on the contextual signals and intracellular gene circuits of a particular cell, this program can drive… read more here.
Keywords: mesenchymal transition; program; transition cancer; epithelial mesenchymal ... See more keywords
Demographic transition - Cancer trends in geriatric population of North India.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of geriatric oncology"
DOI: 10.1016/j.jgo.2018.07.011
Abstract: Developing countries like India are witnessing a demographic transition resulting in population ageing. This population expansion will in future increase the burden of diseases more prevalent in older patients. Since cancer incidence increases with age,… read more here.
Keywords: cancer trends; demographic transition; transition cancer; cancer ... See more keywords
Shape-specific characterization of colorectal adenoma growth and transition to cancer with stochastic cell-based models
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1010831
Abstract: Colorectal adenoma are precursor lesions on the pathway to cancer. Their removal in screening colonoscopies has markedly reduced rates of cancer incidence and death. Generic models of adenoma growth and transition to cancer can guide… read more here.
Keywords: transition cancer; adenoma; cancer; adenoma growth ... See more keywords
Endothelial-to-Mesenchymal Transition in Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00747
Abstract: Cancer is one of the most important causes of morbidity and mortality worldwide. Tumor cells grow in a complex microenvironment constituted of immune, stromal, and vascular cells that supports growth, angiogenesis, and metastasis. Endothelial cells… read more here.
Keywords: mesenchymal transition; endothelial mesenchymal; transition cancer; process ... See more keywords
Epithelial-to-Pericyte Transition in Cancer
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DOI: 10.3390/cancers9070077
Abstract: During epithelial-to-mesenchymal transition (EMT), cells lose epithelial characteristics and acquire mesenchymal properties. These two processes are genetically separable and governed by distinct transcriptional programs, rendering the EMT outputs highly heterogeneous. Our recent study shows that… read more here.
Keywords: transition; epithelial pericyte; transition cancer; pericyte transition ... See more keywords