Generation of In Vitro Model of Epithelial Mesenchymal Transition (EMT) Via the Expression of a Cytoplasmic Mutant Form of Promylocytic Leukemia Protein (PML).
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7401-6_12
Abstract: Epithelial Mesenchymal Transition (EMT) is a key event in cancer progression. During this event, epithelial cancer cells undergo molecular and cellular changes leading to their trans-differentiation into mesenchymal cancer cells that are capable of migration,… read more here.
Keywords: mesenchymal transition; emt; transition emt; epithelial mesenchymal ... See more keywords
Therapeutic implications of cancer epithelial-mesenchymal transition (EMT)
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DOI: 10.1007/s12272-018-01108-7
Abstract: The epithelial-mesenchymal transition (EMT) comprises an essential biological process involving cancer progression as well as initiation. While the EMT has been regarded as a phenotypic conversion from epithelial to mesenchymal cells, recent evidence indicates that… read more here.
Keywords: mesenchymal transition; emt therapeutic; transition emt; epithelial mesenchymal ... See more keywords
GALNTs: master regulators of metastasis-associated epithelial-mesenchymal transition (EMT)?
Sign Up to like & getrecommendations! Published in 2022 at "Glycobiology"
DOI: 10.1093/glycob/cwac014
Abstract: In humans, the UDP-N-α-D galactosamine:polypeptide N-acetylgalactosaminyltransferases family (ppGalNAc-Ts, GalNAc-Ts or GALNTs) comprises 20 isoenzymes. They are responsible for the initial synthesis of α-GalNAc1,3-O-Ser/Thr, or Tn antigen, at initiation of mucin type O-linked glycosylation. This structure… read more here.
Keywords: metastasis; mesenchymal transition; linked glycosylation; transition emt ... See more keywords
CTEN induces epithelial-mesenchymal transition (EMT) and metastasis in non small cell lung cancer cells
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DOI: 10.1371/journal.pone.0198823
Abstract: To explore the effects and mechanism of CTEN (COOH-terminus tensin-like molecule) on EMT, cell migration and invasion of Human lung adenocarcinoma cells. The pCMV-vector, pCMV-CTEN, Control-shRNA, and CTEN-shRNA were transfected into A549 and NCI-H1299 cells… read more here.
Keywords: mesenchymal transition; emt; group; transition emt ... See more keywords
DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells.
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DOI: 10.2220/biomedres.38.221
Abstract: Differentiated embryonic chondrocyte (DEC) 1 has been reported to be involved in cell differentiation, hypoxia response, and cancer progression. Recent studies have demonstrated that hypoxia-inducible factor (HIF)-1α induces epithelial-mesenchymal transition (EMT) in carcinoma cells to… read more here.
Keywords: mesenchymal transition; carcinoma; transition emt; epithelial mesenchymal ... See more keywords
Losartan Alleviates Renal Fibrosis and Inhibits Endothelial-to-Mesenchymal Transition (EMT) Under High-Fat Diet-Induced Hyperglycemia
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.01213
Abstract: The endothelial-to-mesenchymal transition (EMT) of glomerular vascular endothelial cells is considered to be pivotal in diabetic nephropathy (DN). The risk of DN can be decreased by losartan, but the potential molecular mechanism(s) are not fully… read more here.
Keywords: mesenchymal transition; fibrosis; endothelial mesenchymal; transition emt ... See more keywords
Quantifying the Epithelial-to-Mesenchymal Transition (EMT) from Bench to Bedside
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DOI: 10.3390/cancers14051138
Abstract: Simple Summary Cell developmental programs used in wound healing and development such as the epithelial-to-mesenchymal transition (EMT) are frequently coopted by solid tumors to increase motility, plasticity, and invasive characteristics which promote metastasis. Identifying and… read more here.
Keywords: bench bedside; mesenchymal transition; transition emt; epithelial mesenchymal ... See more keywords
MicroRNA Interrelated Epithelial Mesenchymal Transition (EMT) in Glioblastoma
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DOI: 10.3390/genes13020244
Abstract: MicroRNAs (miRNA) are small non-coding RNAs that are 20–23 nucleotides in length, functioning as regulators of oncogenes or tumor suppressor genes. They are molecular modulators that regulate gene expression by suppressing gene translation through gene… read more here.
Keywords: emt; mesenchymal transition; transition emt; epithelial mesenchymal ... See more keywords
Atropine Is a Suppressor of Epithelial–Mesenchymal Transition (EMT) That Reduces Stemness in Drug-Resistant Breast Cancer Cells
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DOI: 10.3390/ijms23179849
Abstract: Atropine (ATR) is extracted from a belladonna plant that belongs to a class of anticholinergic drugs and is therefore involved in the treatment of the overdose of cholinergic drugs or mushroom poisoning. It is a… read more here.
Keywords: mesenchymal transition; breast; transition emt; epithelial mesenchymal ... See more keywords
Extra-Cellular Vesicles Derived from Thyroid Cancer Cells Promote the Epithelial to Mesenchymal Transition (EMT) and the Transfer of Malignant Phenotypes through Immune Mediated Mechanisms
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DOI: 10.3390/ijms24032754
Abstract: Thyroid cancer is the most common endocrine cancer, and its incidence is increasing in many countries around the world. Among thyroid cancers, the papillary thyroid cancer (PTC) histotype is particularly prevalent. A small percentage of… read more here.
Keywords: mesenchymal transition; thyroid cancer; transition emt; epithelial mesenchymal ... See more keywords