Molecular basis for the inhibitory effects of 5-hydroxycyclopenicillone on the conformational transition of Aβ40 monomer
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DOI: 10.1080/07391102.2020.1799863
Abstract: Abstract Previous studies have indicated that 5-hydroxycyclopenicillone (HCP), an active compound derived from marine sponge, could inhibit oligomerization of amyloid β-protein (Aβ). However, the molecular basis for the interaction between HCP and Aβ remains unclear.… read more here.
Keywords: inhibitory effects; molecular basis; hcp; conformational transition ... See more keywords