Insight into the transition between the open and closed conformations of Thermus thermophilus carboxypeptidase.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.167
Abstract: Carboxypeptidase cleaves the C-terminal amino acid residue from proteins and peptides. Here, we report the functional and structural characterizations of carboxypeptidase belonging to the M32 family from the thermophilic bacterium Thermus thermophilus HB8 (TthCP). TthCP… read more here.
Keywords: open closed; carboxypeptidase; thermus thermophilus; closed states ... See more keywords
Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27686-7
Abstract: Eukaryotic topoisomerases I (TOP1) are ubiquitous enzymes removing DNA torsional stress. However, there is little data concerning the three-dimensional structure of TOP1 in the absence of DNA, nor how the DNA molecule can enter/exit its… read more here.
Keywords: dna; open closed; conformation; topoisomerase top1 ... See more keywords
Intensive Care Neonates and Evidence to Support the Elimination of Hats for Safe Sleep
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Neonatal Care"
DOI: 10.1097/anc.0000000000000695
Abstract: Background: Although the incidence of sudden unexplained infant deaths has decreased over time with the use of safe sleep practices, one area that remains unclear is the safety of hats during infant sleep. Purpose: Decrease… read more here.
Keywords: crib; open crib; intensive care; safe sleep ... See more keywords
Water inrush characteristics and hazard effects during the transition from open-pit to underground mining: a case study
Sign Up to like & getrecommendations! Published in 2019 at "Royal Society Open Science"
DOI: 10.1098/rsos.181402
Abstract: During the transition from open-pit to underground mining in iron ore mines, water inrush is a prominent problem for mine safety and production. In this paper, a comprehensive method that incorporates hydrochemical analysis and numerical… read more here.
Keywords: open pit; water inrush; water; pit underground ... See more keywords