PRDM14-CtBP1/2-PRC2 complex regulates transcriptional repression during transition from primed to naïve pluripotency.
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DOI: 10.1242/jcs.240176
Abstract: The pluripotency-associated transcriptional network is regulated by a core circuitry of transcription factors. The PR domain-containing protein, PRDM14, maintains pluripotency by activating and repressing transcription in a target gene-dependent manner. However, the mechanisms underlying dichotomic… read more here.
Keywords: transition primed; primed pluripotency; ctbp1; pluripotency ... See more keywords