Ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria
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DOI: 10.1126/sciadv.ade8582
Abstract: The mechanism(s) of how bacteria acquire tolerance and then resistance to antibiotics remains poorly understood. Here, we show that glucose abundance decreases progressively as ampicillin-sensitive strains acquire resistance to ampicillin. The mechanism involves that ampicillin… read more here.
Keywords: glucose metabolism; resistance; tolerance resistance; transition tolerance ... See more keywords