Fingolimod induces BAFF and expands circulating transitional B cells without activating memory B cells and plasma cells in multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.10.009
Abstract: Patients with multiple sclerosis (MS) who are treated with fingolimod have an increased proportion of transitional B cells in the circulation, but the underlying mechanism is not known. We hypothesized that B cell-activating factor of… read more here.
Keywords: transitional cells; memory cells; cells plasma; fingolimod induces ... See more keywords
Marked elevation of circulating CD19+CD38hiCD24hi transitional B cells give protection against neonatal sepsis.
Sign Up to like & getrecommendations! Published in 2018 at "Pediatrics and neonatology"
DOI: 10.1016/j.pedneo.2017.10.005
Abstract: BACKGROUND Adequate functions of immunoregulation, mediated by regulatory cells such as IL-10 producing CD19+CD38hiCD24hi transitional B cells (Trans), play an important role in control of excessive inflammatory response. Yet, the role of Trans in neonatal… read more here.
Keywords: sepsis; neonatal sepsis; cd19 cd38hicd24hi; transitional cells ... See more keywords
Semisoft clustering of single-cell data
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1817715116
Abstract: Significance Growth typically involves differentiation of cells from progenitors into more specialized descendants, often involving lineages of pure and transitional cells to achieve final form. Recent technology has enabled estimation of gene expression profiles of… read more here.
Keywords: pure; semisoft clustering; transitional cells; pure cells ... See more keywords
Transitional B cells involved in autoimmunity and their impact on neuroimmunological diseases
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DOI: 10.1186/s12967-020-02289-w
Abstract: Transitional B cells (TrB cells) represent a crucial link between immature B cells in the bone marrow and mature peripheral B cells. Although TrB cells represent one of the regulatory B cell subpopulations in healthy… read more here.
Keywords: transitional cells; involved autoimmunity; trb cells; neuroimmunological diseases ... See more keywords