Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force.
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DOI: 10.1073/pnas.2207615120
Abstract: Contraction in striated muscle is initiated by calcium binding to troponin complexes, but it is now understood that dynamic transition of myosin between resting, ordered OFF states on thick filaments and active, disordered ON states… read more here.
Keywords: myosin relaxed; transitions myosin; muscle; structural transitions ... See more keywords