YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA
Sign Up to like & getrecommendations! Published in 2017 at "Cell Research"
DOI: 10.1038/cr.2017.15
Abstract: N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and tissue development. It regulates multiple steps throughout the RNA life cycle including RNA processing,… read more here.
Keywords: translation decay; ythdf3; m6a modified; translation ... See more keywords
mRNA 5′ terminal sequences drive 200-fold differences in expression through effects on synthesis, translation and decay
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1010532
Abstract: mRNA regulatory sequences control gene expression at multiple levels including translation initiation and mRNA decay. The 5′ terminal sequences of mRNAs have unique regulatory potential because of their proximity to key post-transcriptional regulators. Here we… read more here.
Keywords: 200 fold; expression; terminal sequences; translation decay ... See more keywords