Molecular simulations of the ribosome and associated translation factors.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2017.11.003
Abstract: The ribosome is a macromolecular complex which is responsible for protein synthesis in all living cells according to their transcribed genetic information. Using X-ray crystallography and, more recently, cryo-electron microscopy (cryo-EM), the structure of the… read more here.
Keywords: information; molecular simulations; simulations ribosome; translation factors ... See more keywords
The translation factors of Drosophila melanogaster
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DOI: 10.1080/19336934.2016.1220464
Abstract: ABSTRACT Synthesis of polypeptides from mRNA (translation) is a fundamental cellular process that is coordinated and catalyzed by a set of canonical ‘translation factors’. Surprisingly, the translation factors of Drosophila melanogaster have not yet been… read more here.
Keywords: ontology; translation factors; drosophila melanogaster; translation ... See more keywords
The Structural Dynamics of Translation.
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DOI: 10.1146/annurev-biochem-071921-122857
Abstract: Accurate protein synthesis (translation) relies on translation factors that rectify ribosome fluctuations into a unidirectional process. Understanding this process requires structural characterization of the ribosome and translation-factor dynamics. In the 2000s, crystallographic studies determined high-resolution… read more here.
Keywords: dynamics translation; microscopy; translation factors; biochemistry ... See more keywords