The basal translation rate of authentic HIV-1 RNA is regulated by 5’UTR nt-pairings at junction of R and U5
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-06883-9
Abstract: The paradigm protein synthesis rate is regulated by structural complexity of the 5′untranslated region (UTR) derives from bacterial and other riboswitches. In-solution, HIV-1 5′UTR forms two interchangeable long-range nucleotide (nt) -pairings, one sequesters the gag… read more here.
Keywords: basal translation; translation rate; translation; rate ... See more keywords
A novel active transposon creates allelic variation through altered translation rate to influence protein abundance
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1195
Abstract: Abstract Protein translation is tightly and precisely controlled by multiple mechanisms including upstream open reading frames (uORFs), but the origins of uORFs and their role in maize are largely unexplored. In this study, an active… read more here.
Keywords: protein abundance; translation rate; influence protein; abundance ... See more keywords
Translation rate underpins specific targeting of N-terminal transmembrane proteins to mitochondria.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of integrative plant biology"
DOI: 10.1111/jipb.13475
Abstract: Protein biogenesis is a complex process, and complexity is greatly increased in eukaryotic cells through specific targeting of proteins to different organelles. To direct targeting, organellar proteins carry an organelle-specific targeting signal for recognition by… read more here.
Keywords: rate underpins; translation rate; transmembrane; mitochondrial targeting ... See more keywords