Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock
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DOI: 10.1093/nar/gkz261
Abstract: Abstract The non-canonical initiation factor DENR promotes translation reinitiation on mRNAs harbouring upstream open reading frames (uORFs). Moreover, DENR depletion shortens circadian period in mouse fibroblasts, suggesting involvement of uORF usage and reinitiation in clock… read more here.
Keywords: charting denr; clock; reinitiation; translation reinitiation ... See more keywords