In vitro reconstitution of translational arrest pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Methods"
DOI: 10.1016/j.ymeth.2017.12.018
Abstract: Protein translation is tightly regulated to ensure high-fidelity expression of genetic information. Various conditions cause ribosomes to stall while synthesizing new proteins. Different types of translational arrest initiate specific mRNA surveillance, protein quality control, and… read more here.
Keywords: vitro reconstitution; arrest pathways; translational arrest; arrest ... See more keywords
Probing Interplays between Human XBP1u Translational Arrest Peptide and 80S Ribosome
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Chemical Theory and Computation"
DOI: 10.1021/acs.jctc.1c00796
Abstract: The ribosome stalling mechanism is a crucial biological process, yet its atomistic underpinning is still elusive. In this framework, the human XBP1u translational arrest peptide (AP) plays a central role in regulating the unfolded protein… read more here.
Keywords: arrest; xbp1u translational; arrest peptide; translational arrest ... See more keywords