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Published in 2021 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2021.01.028
Abstract: Translational control plays a fundamental role in the regulation of gene expression in eukaryotes. Modulating translational efficiency allows the cell to fine-tune the expression of genes, spatially control protein localization, and trigger fast responses to…
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Keywords:
reprogramming translation;
translation;
translational efficiency;
gene ... See more keywords
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Published in 2017 at "Genome research"
DOI: 10.1101/gr.202150.115
Abstract: Translational efficiency is subject to extensive regulation. However, the factors influencing such regulation are poorly understood. In Caenorhabditis elegans, 62% of genes are trans-spliced to a specific spliced leader (SL1), which replaces part of the…
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Keywords:
enhances translational;
trans spliced;
translational efficiency;
sl1 trans ... See more keywords
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Published in 2018 at "Genome research"
DOI: 10.1101/gr.231506.117
Abstract: 3' UTRs play important roles in the gene regulation network via their influence on mRNA stability, translational efficiency, and subcellular localization. For a given gene, 3' UTRs of different lengths generated by alternative polyadenylation (APA)…
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Keywords:
translational efficiency;
regulation protein;
mirnas regulation;
alternative polyadenylation ... See more keywords
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Published in 2022 at "RNA"
DOI: 10.1261/rna.079046.121
Abstract: Neurons provide a rich setting for studying post-transcriptional control. Here, we investigate the landscape of translational control in neurons and search for mRNA features that explain differences in translational efficiency (TE), considering the interplay between…
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Keywords:
micrornas neuronal;
translational efficiency;
mrna;
control ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0178189
Abstract: To further our understanding of the somatic genetic basis of uveal melanoma, we sequenced the protein-coding regions of 52 primary tumors and 3 liver metastases together with paired normal DNA. Known recurrent mutations were identified…
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Keywords:
uveal melanoma;
mutant eif1ax;
translational efficiency;
eif1ax ... See more keywords
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Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8090938
Abstract: Protein synthesis is strictly regulated during replicative aging in yeast, but global translational regulation during replicative aging is poorly characterized. To conduct ribosome profiling during replicative aging, we collected a large number of dividing aged…
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Keywords:
translational efficiency;
translational regulation;
replicative aging;
regulation replicative ... See more keywords