Reciprocity of Cell Mechanics with Extracellular Stimuli: Emerging Opportunities for Translational Medicine.
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DOI: 10.1002/smll.202107305
Abstract: Human cells encounter dynamic mechanical cues in healthy and diseased tissues, which regulate their molecular and biophysical phenotype, including intracellular mechanics as well as force generation. Recent developments in bio/nanomaterials and microfluidics permit exquisitely sensitive… read more here.
Keywords: mechanics; medicine; cell mechanics; translational medicine ... See more keywords
Commentary: Translational Medicine and Neurosurgery: Chance and the Prepared Mind.
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DOI: 10.1093/neuros/nyy352
Abstract: Copyright C © 2018 by the Congress of Neurological Surgeons T he term “translational medicine” has become an essential part of the contemporary discussion about priorities in the funding of medical and healthcare research, particularly… read more here.
Keywords: medicine; research; translational medicine; number ... See more keywords
Paper of note in Science Translational Medicine 9 (373)
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DOI: 10.1126/scisignal.aam8057
Abstract: This week’s paper describes a drug that inhibits multiple growth factor pathways and may effectively treat patients with retinopathies. This week’s paper describes a drug that inhibits multiple growth factor pathways and may effectively treat… read more here.
Keywords: medicine; note science; paper; translational medicine ... See more keywords
Papers of note in Science Translational Medicine 9 (376)
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DOI: 10.1126/scisignal.aam9533
Abstract: This week’s articles describe a free radical scavenger for treating hypertension; an engineered bacterium as a cancer immunotherapy; commensal bacteria that protect newborn mice from pneumonia; and a form of gastrointestinal E. coli that triggers… read more here.
Keywords: medicine; papers note; science; note science ... See more keywords
Papers of note in Science Translational Medicine 9 (386)
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DOI: 10.1126/scisignal.aan4922
Abstract: This week’s articles describe a new hydrogel that promotes chronic wound healing and a way to limit intestinal tissue damage from radiation, chemo, or hematopoietic cell transplant therapies. This week’s articles describe a new hydrogel… read more here.
Keywords: papers note; medicine; medicine 386; note science ... See more keywords
Papers of note in Science Translational Medicine 9 (387)
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DOI: 10.1126/scisignal.aan5399
Abstract: This week’s articles reveal a new treatment for malaria and an adjunct therapy that may reduce the hematologic toxicity of chemotherapy. This week’s articles reveal a new treatment for malaria and an adjunct therapy that… read more here.
Keywords: medicine; papers note; science; note science ... See more keywords
Papers of note in Science Translational Medicine 9 (393)
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DOI: 10.1126/scisignal.aao0286
Abstract: This week’s articles describe a new combination therapy for BRCA1-mutant breast cancer and a new therapeutic target in patients with the ectopic calcification disease PXE. This week’s articles describe a new combination therapy for BRCA1-mutant… read more here.
Keywords: medicine; papers note; science; note science ... See more keywords
Papers of note in Science Translational Medicine 9 (409)
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DOI: 10.1126/scisignal.aaq0767
Abstract: This week’s articles describe a stem cell–based therapy for chronic kidney disease and targets for treating diabetic nerve pain and acute respiratory distress in critically ill patients. This week’s articles describe a stem cell–based therapy… read more here.
Keywords: medicine; papers note; science; note science ... See more keywords
Papers of note in Science Translational Medicine 9 (410)
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DOI: 10.1126/scisignal.aaq0801
Abstract: This week’s article and a review describe ways to potentially improve immunotherapy for cancer patients. This week’s article and a review describe ways to potentially improve immunotherapy for cancer patients. read more here.
Keywords: papers note; medicine; note science; translational medicine ... See more keywords
Papers of note in Science Translational Medicine 9 (412)
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DOI: 10.1126/scisignal.aar2008
Abstract: This week’s articles describe ways to potentially treat obesity-associated disorders and prevent sepsis. This week’s articles describe ways to potentially treat obesity-associated disorders and prevent sepsis. read more here.
Keywords: medicine; papers note; science; note science ... See more keywords
Translational Medicine in the Era of Big Data and Machine Learning.
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DOI: 10.1161/circresaha.118.313944
Abstract: Basic research in cardiovascular medicine has yielded dramatic insights into physiology, leading to therapeutic advances and a significant decrease in cardiovascular mortality for the past 50 years. Nonetheless, it is increasingly recognized that even highly… read more here.
Keywords: medicine; big data; machine learning; translational medicine ... See more keywords