Opportunities for quantitative translational modelling in Oncology.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.1963
Abstract: A two-day meeting was held by members of the UK Quantitative Systems Pharmacology Network [] in November 2018 on the topic of Translational Challenges in Oncology. Participants from a wide range of backgrounds were invited… read more here.
Keywords: opportunities quantitative; pharmacology; translational modelling; oncology ... See more keywords
How translational modelling in oncology needs to get the mechanism just right.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and translational science"
DOI: 10.1111/cts.13183
Abstract: Translational model-based approaches have played a role in increasing success in the development of novel anti-cancer treatments. However, despite this, significant translational uncertainty remains from animal models to patients. Optimisation of dose and scheduling (regimen)… read more here.
Keywords: modelling oncology; mechanism; oncology needs; needs get ... See more keywords