Spontaneous, co-translational peptide macrocyclization using p-cyanoacetylene-phenylalanine.
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DOI: 10.1039/d2cc01148d
Abstract: Peptide macrocycles (PMCs) are increasingly popular for the development of inhibitors of protein-protein interactions (PPIs). Large libraries of PMCs are accessible using display technologies like mRNA display and phage display. These technologies require macrocyclization chemistries… read more here.
Keywords: spontaneous translational; peptide; translational peptide; macrocyclization using ... See more keywords