The humanized mouse: Emerging translational potential
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DOI: 10.1002/mc.23195
Abstract: The humanized mouse (HM) has emerged as a valuable animal model in cancer research. Engrafted with components of a human immune system and subsequently implanted with tumor tissue from cell lines or in the form… read more here.
Keywords: mouse emerging; humanized mouse; emerging translational; translational potential ... See more keywords
Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma
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DOI: 10.2217/cns-2017-0019
Abstract: In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this… read more here.
Keywords: glioma; mutation subtypes; site 132; translational potential ... See more keywords
Translational potential of base-editing tools for gene therapy of monogenic diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.942440
Abstract: Millions of people worldwide have rare genetic diseases that are caused by various mutations in DNA sequence. Classic treatments of rare genetic diseases are often ineffective, and therefore great hopes are placed on gene-editing methods.… read more here.
Keywords: potential base; monogenic diseases; base editing; translational potential ... See more keywords
Clinical Translational Potential in Skin Wound Regeneration for Adipose-Derived, Blood-Derived, and Cellulose Materials: Cells, Exosomes, and Hydrogels
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DOI: 10.3390/biom10101373
Abstract: Acute and chronic skin wounds due to burns, pressure injuries, and trauma represent a substantial challenge to healthcare delivery with particular impacts on geriatric, paraplegic, and quadriplegic demographics worldwide. Nevertheless, the current standard of care… read more here.
Keywords: wound; skin; clinical translational; potential skin ... See more keywords