The humanized mouse: Emerging translational potential
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23195
Abstract: The humanized mouse (HM) has emerged as a valuable animal model in cancer research. Engrafted with components of a human immune system and subsequently implanted with tumor tissue from cell lines or in the form… read more here.
Keywords: mouse emerging; humanized mouse; emerging translational; translational potential ... See more keywords
Unlocking the Translational Potential of Nanophotonic Biosensors: Perspectives on Application-Guided Design
Sign Up to like & getrecommendations! Published in 2025 at "ACS Photonics"
DOI: 10.1021/acsphotonics.5c00838
Abstract: Biochemical sensing platforms have become indispensable to critical decision-making across healthcare, security, and industryî—¸delivering essential data that powers AI systems and shaping our modern lifestyles. This growing reliance on biosensors has elevated expectations, creating demand… read more here.
Keywords: application guided; translational potential; guided design; nanophotonic biosensors ... See more keywords
Abstract Wed012: Assessing Mouse Transverse Aortic Constriction Studies in AHA Journals for Reproducibility and Translational Potential
Sign Up to like & getrecommendations! Published in 2025 at "Circulation Research"
DOI: 10.1161/res.137.suppl_1.wed012
Abstract: Background: Mouse transverse aortic constriction (TAC) is a common technique to study heart failure. The hemodynamic severity of TAC is a main factor affecting cardiac outcomes with higher pressure gradients causing more fibrosis and heart… read more here.
Keywords: tac; severity; translational potential; mouse transverse ... See more keywords
Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma
Sign Up to like & getrecommendations! Published in 2018 at "CNS Oncology"
DOI: 10.2217/cns-2017-0019
Abstract: In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this… read more here.
Keywords: glioma; mutation subtypes; site 132; translational potential ... See more keywords
Translational potential of base-editing tools for gene therapy of monogenic diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.942440
Abstract: Millions of people worldwide have rare genetic diseases that are caused by various mutations in DNA sequence. Classic treatments of rare genetic diseases are often ineffective, and therefore great hopes are placed on gene-editing methods.… read more here.
Keywords: potential base; monogenic diseases; base editing; translational potential ... See more keywords
Clinical Translational Potential in Skin Wound Regeneration for Adipose-Derived, Blood-Derived, and Cellulose Materials: Cells, Exosomes, and Hydrogels
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10101373
Abstract: Acute and chronic skin wounds due to burns, pressure injuries, and trauma represent a substantial challenge to healthcare delivery with particular impacts on geriatric, paraplegic, and quadriplegic demographics worldwide. Nevertheless, the current standard of care… read more here.
Keywords: wound; skin; clinical translational; potential skin ... See more keywords
Animal Toxins: Biodiscovery, Mechanistic Insights and Translational Potential
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DOI: 10.3390/toxins16030130
Abstract: Nature abounds with an unprecedented diversity of biomolecular innovation [...]. read more here.
Keywords: mechanistic insights; animal toxins; toxins biodiscovery; biodiscovery mechanistic ... See more keywords