The translational regulation of maternal mRNAs in time and space
Sign Up to like & getrecommendations! Published in 2018 at "Febs Letters"
DOI: 10.1002/1873-3468.13183
Abstract: Since their discovery, the study of maternal mRNAs has led to the identification of mechanisms underlying their spatiotemporal regulation within the context of oogenesis and early embryogenesis. Following synthesis in the oocyte, maternal mRNAs are… read more here.
Keywords: time; regulation maternal; maternal mrnas; translational regulation ... See more keywords
Post‐translational regulation of muscle growth, muscle aging and sarcopenia
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13241
Abstract: Skeletal muscle makes up 30–40% of the total body mass. It is of great significance in maintaining digestion, inhaling and exhaling, sustaining body posture, exercising, protecting joints and many other aspects. Moreover, muscle is also… read more here.
Keywords: regulation muscle; translational regulation; post translational; muscle ... See more keywords
The role of mRNA structure in bacterial translational regulation
Sign Up to like & getrecommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1370
Abstract: The characteristics of bacterial messenger RNAs (mRNAs) that influence translation efficiency provide many convenient handles for regulation of gene expression, especially when coupled with the processes of transcription termination and mRNA degradation. An mRNA's structure,… read more here.
Keywords: translational regulation; mrna structure; bacterial translational; structure ... See more keywords
A Ribo-Seq Method to Study Genome-Wide Translational Regulation in Plants.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2297-1_6
Abstract: Protein production from mRNA is one of the fundamental molecular processes in a cell. Accurate genome-wide information on the levels of translation and ribosome distribution on mRNA can be gathered by carrying out ribosome footprinting,… read more here.
Keywords: translational regulation; ribo seq; genome wide; seq method ... See more keywords
Translational Regulation in the Mammalian Oocyte.
Sign Up to like & getrecommendations! Published in 2017 at "Results and problems in cell differentiation"
DOI: 10.1007/978-3-319-60855-6_12
Abstract: Fully grown oocytes arrest meiosis at prophase I and deposit maternal RNAs. A subset of maternal transcripts is stored in a dormant state in the oocyte, and the timely driven translation of specific mRNAs guides… read more here.
Keywords: regulation mammalian; progression; mammalian oocyte; translational regulation ... See more keywords
Elucidating post-translational regulation of mouse CREB3 in Neuro2a cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3333-9
Abstract: CREB3 is an ER membrane-bound transcription factor; however, post-translational regulation of CREB3, including expression, processing, and activation, is not fully characterized. We therefore constructed several types of mouse CREB3 expression genes and elucidated their expression… read more here.
Keywords: creb3; mouse creb3; post translational; expression ... See more keywords
Translational regulation is a key determinant of the cellular response to benzo[a]pyrene.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2018.06.009
Abstract: Translational control is a cellular response mechanism which initiates adaptation during various stress situations. Here, we investigated the role of translational control after benzo[a]pyrene (BaP) exposure in primary mouse hepatocytes. Translated mRNAs were separated and… read more here.
Keywords: benzo pyrene; cellular response; translational regulation; regulation ... See more keywords
Widespread pre-translational regulation of the inclusion of signal peptides in human proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Genomics"
DOI: 10.1016/j.ygeno.2017.01.001
Abstract: Signal peptides (SP) are cleavable N-terminal protein motifs used co-translationally for entry of nascent polypeptides into the secretory pathway. Their co-translational cleavage prevents their extensive post-translational regulation and flexibility in their usage is made possible… read more here.
Keywords: regulation inclusion; inclusion; signal peptides; pre translational ... See more keywords
Synthetic Translational Regulation by Protein-Binding RNA Origami Scaffolds
Sign Up to like & getrecommendations! Published in 2022 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.1c00608
Abstract: Rational design approaches for the regulation of gene expression are expanding the synthetic biology toolbox. However, only a few tools for regulating gene expression at the translational level have been developed. Here, we devise an… read more here.
Keywords: translational regulation; rna origami; origami scaffolds; regulation ... See more keywords
Post-translational regulation of metabolic checkpoints in plant tetrapyrrole biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erac203
Abstract: Abstract Tetrapyrrole biosynthesis produces metabolites that are essential for critical reactions in photosynthetic organisms, including chlorophylls, heme, siroheme, phytochromobilins, and their derivatives. Due to the paramount importance of tetrapyrroles, a better understanding of the complex… read more here.
Keywords: biosynthesis; translational regulation; post translational; metabolic checkpoints ... See more keywords
Translational co-regulation of a ligand and inhibitor by a conserved RNA element
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx938
Abstract: Abstract In many organisms, transcriptional and post-transcriptional regulation of components of pathways or processes has been reported. However, to date, there are few reports of translational co-regulation of multiple components of a developmental signaling pathway.… read more here.
Keywords: rna element; ybx1; ligand; translational regulation ... See more keywords