Ribosome collisions alter frameshifting at translational reprogramming motifs in bacterial mRNAs
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1910613116
Abstract: Significance Ribosomes move along mRNAs in 3-nucleotide steps as they interpret codons that specify which amino acid is required at each position in the protein. There are multiple examples of genes with DNA sequences that… read more here.
Keywords: translational reprogramming; collisions alter; ribosome collisions; reprogramming motifs ... See more keywords
PO-151 Variation of ribosome composition and translational reprogramming during human mammary epithelial-to-mesenchymal transition
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.192
Abstract: Introduction It has been thought for a long time that ribosome, the machinery translating mRNAs into proteins, displays invariable intrinsic translational activity. However, it recently emerged that ribosome can act as a direct regulator of… read more here.
Keywords: translational reprogramming; epithelial mesenchymal; composition; cancer ... See more keywords
Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17597
Abstract: 5-Fluorouracil (5-FU) is a widely used chemotherapeutic drug in colorectal cancer. Previous studies showed that 5-FU modulates RNA metabolism and mRNA expression. In addition, it has been reported that 5-FU incorporates into the RNAs constituting… read more here.
Keywords: reprogramming colorectal; translational reprogramming; colorectal cancer; translation ... See more keywords