Bioreactor-scale cell performance and protein production can be substantially increased by using a secretion signal that drives co-translational translocation in Pichia pastoris.
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DOI: 10.1016/j.nbt.2020.09.001
Abstract: Pichia pastoris (Komagataella spp.) has become one of the most important host organisms for production of heterologous proteins of biotechnological interest, many of them extracellular. The protein secretion pathway has been recognized as a limiting… read more here.
Keywords: protein; secretion signal; secretion; production ... See more keywords