Single-molecule studies contrast ordered DNA replication with stochastic translesion synthesis
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DOI: 10.7554/elife.32177
Abstract: High fidelity replicative DNA polymerases are unable to synthesize past DNA adducts that result from diverse chemicals, reactive oxygen species or UV light. To bypass these replication blocks, cells utilize specialized translesion DNA polymerases that… read more here.
Keywords: single molecule; dna; translesion; translesion polymerases ... See more keywords