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   Articles with "translocation" as a keyword



Electrical pulse stimulation induces GLUT4 translocation in a Rac‐Akt‐dependent manner in C2C12 myotubes

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recommendations! Published in 2018 at "FEBS Letters"

DOI: 10.1002/1873-3468.12982

Abstract: Muscle contraction increases skeletal muscle glucose uptake, but the underlying mechanisms are not fully elucidated. While important for insulin‐stimulated glucose uptake, the role of Akt in contraction‐stimulated muscle glucose uptake is controversial. In our study,… read more here.

Keywords: electrical pulse; pulse stimulation; glut4 translocation; translocation ... See more keywords

On the role of ubiquinone in the proton translocation mechanism of respiratory complex I

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14506

Abstract: Complex I converts oxidoreduction energy into a proton electrochemical gradient across the inner mitochondrial or bacterial cell membrane. This gradient is the primary source of energy for aerobic synthesis of ATP. Oxidation of reduced nicotinamide… read more here.

Keywords: proton translocation; translocation; role ubiquinone; membrane ... See more keywords

Conformationally Confined Emissive Cationic Macrocycle with Photocontrolled Organelle‐Specific Translocation

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202201962

Abstract: The optimization of molecular conformation and aggregation modes is of great significance in creation of new luminescent materials for biochemical research and medical diagnostics. Herein, a highly emissive macrocycle (1) is reported, which is constructed… read more here.

Keywords: conformationally confined; organelle specific; cationic macrocycle; translocation ... See more keywords

Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202400794

Abstract: Sphingolipids play vital roles in metabolism and regulation. Previously, the aryl hydrocarbon receptor (AHR), a ligand‐activated transcription factor, was reported to directly regulate ceramide synthesis genes by binding to their promoters. Herein, sphingosine kinase 2… read more here.

Keywords: activation; target gene; sphk2; nuclear translocation ... See more keywords

Apoptosis detection via automated algorithms to analyze biomarker translocation in reporter cells

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recommendations! Published in 2020 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.27280

Abstract: Rapid, efficient, and robust quantitative analyses of dynamic apoptotic events are essential in a high‐throughput screening workflow. Currently used methods have several bottlenecks, specifically, limitations in available fluorophores for downstream assays and misinterpretation of statistical… read more here.

Keywords: reporter; cell lines; reporter cells; apoptotic events ... See more keywords

Lesser prairie‐chicken dispersal after translocation: Implications for restoration and population connectivity

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recommendations! Published in 2024 at "Ecology and Evolution"

DOI: 10.1002/ece3.10871

Abstract: Abstract Conservation translocations are frequently inhibited by extensive dispersal after release, which can expose animals to dispersal‐related mortality or Allee effects due to a lack of nearby conspecifics. However, translocation‐induced dispersals also provide opportunities to… read more here.

Keywords: release; lesser prairie; prairie chickens; dispersal ... See more keywords
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Concentration effects on capture rate and translocation configuration of nanopore‐based DNA detection

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recommendations! Published in 2020 at "ELECTROPHORESIS"

DOI: 10.1002/elps.202000016

Abstract: Nanopore is a kind of powerful tool to detect single molecules and investigate fundamental biological processes. In biological cells or real detection systems, concentration of DNA molecules is various. Here, we report an experimental study… read more here.

Keywords: concentration; translocation; dna; capture rate ... See more keywords

When Fluorescence Is not a Particle: The Tissue Translocation of Microplastics in Daphnia magna Seems an Artifact.

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recommendations! Published in 2019 at "Environmental toxicology and chemistry"

DOI: 10.1002/etc.4436

Abstract: Previous research reported the translocation of nano- and microplastics from the gastrointestinal tract to tissues in Daphnia magna, most prominently of fluorescent polystyrene beads to lipid droplets. For particles >300 nm, such transfer is biologically… read more here.

Keywords: daphnia magna; fluorescence; study; tissue ... See more keywords

A novel VCP::TFE3 gene fusion resulting from t(X;9)(p11.23;p13.3) chromosome translocation in TFE3 rearranged renal cancer cell carcinoma

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recommendations! Published in 2023 at "Genes"

DOI: 10.1002/gcc.23127

Abstract: Renal cell carcinoma (RCC) with rearrangement of transcription factor for immunoglobulin heavy‐chain enhancer 3 (TFE3; TFE3‐rearranged RCC) at Xp11.2 is a rare tumor entity but the most frequent among the microphthalmia transcription factor family translocation… read more here.

Keywords: cell carcinoma; translocation; vcp tfe3; tfe3 rearranged ... See more keywords

A novel t(X;21)(p11.4;q22.12) translocation adds to the role of BCOR and RUNX1 in myelodysplastic syndromes and acute myeloid leukemias

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recommendations! Published in 2024 at "Genes"

DOI: 10.1002/gcc.23235

Abstract: In myeloid neoplasms, both fusion genes and gene mutations are well‐established events identifying clinicopathological entities. In this study, we present a thus far undescribed t(X;21)(p11.4;q22.12) in five cases with myelodysplastic syndrome (MDS) or acute myeloid… read more here.

Keywords: runx1; acute myeloid; bcor; p11 q22 ... See more keywords

Multi‐omics analysis reveals multiple mechanisms causing Prader–Willi like syndrome in a family with a X;15 translocation

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recommendations! Published in 2022 at "Human Mutation"

DOI: 10.1002/humu.24440

Abstract: Prader–Willi syndrome (PWS; MIM# 176270) is a neurodevelopmental disorder caused by the loss of expression of paternally imprinted genes within the PWS region located on 15q11.2. It is usually caused by either maternal uniparental disomy… read more here.

Keywords: translocation; multi omics; prader willi; omics analysis ... See more keywords