Electrical pulse stimulation induces GLUT4 translocation in a Rac‐Akt‐dependent manner in C2C12 myotubes
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.12982
Abstract: Muscle contraction increases skeletal muscle glucose uptake, but the underlying mechanisms are not fully elucidated. While important for insulin‐stimulated glucose uptake, the role of Akt in contraction‐stimulated muscle glucose uptake is controversial. In our study,… read more here.
Keywords: electrical pulse; pulse stimulation; glut4 translocation; translocation ... See more keywords
On the role of ubiquinone in the proton translocation mechanism of respiratory complex I
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14506
Abstract: Complex I converts oxidoreduction energy into a proton electrochemical gradient across the inner mitochondrial or bacterial cell membrane. This gradient is the primary source of energy for aerobic synthesis of ATP. Oxidation of reduced nicotinamide… read more here.
Keywords: proton translocation; translocation; role ubiquinone; membrane ... See more keywords
Conformationally Confined Emissive Cationic Macrocycle with Photocontrolled Organelle‐Specific Translocation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201962
Abstract: The optimization of molecular conformation and aggregation modes is of great significance in creation of new luminescent materials for biochemical research and medical diagnostics. Herein, a highly emissive macrocycle (1) is reported, which is constructed… read more here.
Keywords: conformationally confined; organelle specific; cationic macrocycle; translocation ... See more keywords
Apoptosis detection via automated algorithms to analyze biomarker translocation in reporter cells
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27280
Abstract: Rapid, efficient, and robust quantitative analyses of dynamic apoptotic events are essential in a high‐throughput screening workflow. Currently used methods have several bottlenecks, specifically, limitations in available fluorophores for downstream assays and misinterpretation of statistical… read more here.
Keywords: reporter; cell lines; reporter cells; apoptotic events ... See more keywords
Concentration effects on capture rate and translocation configuration of nanopore‐based DNA detection
Sign Up to like & getrecommendations! Published in 2020 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202000016
Abstract: Nanopore is a kind of powerful tool to detect single molecules and investigate fundamental biological processes. In biological cells or real detection systems, concentration of DNA molecules is various. Here, we report an experimental study… read more here.
Keywords: concentration; translocation; dna; capture rate ... See more keywords
When Fluorescence Is not a Particle: The Tissue Translocation of Microplastics in Daphnia magna Seems an Artifact.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.4436
Abstract: Previous research reported the translocation of nano- and microplastics from the gastrointestinal tract to tissues in Daphnia magna, most prominently of fluorescent polystyrene beads to lipid droplets. For particles >300 nm, such transfer is biologically… read more here.
Keywords: daphnia magna; fluorescence; study; tissue ... See more keywords
A novel VCP::TFE3 gene fusion resulting from t(X;9)(p11.23;p13.3) chromosome translocation in TFE3 rearranged renal cancer cell carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.1002/gcc.23127
Abstract: Renal cell carcinoma (RCC) with rearrangement of transcription factor for immunoglobulin heavy‐chain enhancer 3 (TFE3; TFE3‐rearranged RCC) at Xp11.2 is a rare tumor entity but the most frequent among the microphthalmia transcription factor family translocation… read more here.
Keywords: cell carcinoma; translocation; vcp tfe3; tfe3 rearranged ... See more keywords
Multi‐omics analysis reveals multiple mechanisms causing Prader–Willi like syndrome in a family with a X;15 translocation
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24440
Abstract: Prader–Willi syndrome (PWS; MIM# 176270) is a neurodevelopmental disorder caused by the loss of expression of paternally imprinted genes within the PWS region located on 15q11.2. It is usually caused by either maternal uniparental disomy… read more here.
Keywords: translocation; multi omics; prader willi; omics analysis ... See more keywords
Translocation and activation of sphingosine kinase 1 by ceramide‐1‐phosphate
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27818
Abstract: Sphingosine kinases (SphKs) and ceramide kinase (CerK) phosphorylate sphingosine to sphingosine‐1‐phosphate (S1P) and ceramide to ceramide‐1‐phosphate (C1P), respectively. S1P and C1P are bioactive lipids that regulate cell fate/function and human health/diseases. The translocation and activity… read more here.
Keywords: sphk1; ceramide; c1p; translocation ... See more keywords
PTHrP promotes development of mouse preimplantation embryos through the AKT/cyclin D1 pathway and nuclear translocation of HDAC4
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30362
Abstract: Parathyroid hormone‐related protein (PTHrP), the main cause of humoral hypercalcemia in malignancies, promotes cell proliferation and delays terminal cell maturation during embryonic development. Our previous study reported that PTHrP plays important roles in blastocyst formation,… read more here.
Keywords: pthrp; hdac4; embryonic development; preimplantation ... See more keywords
Distinguishing functional from structural roles of conserved pore residues during formate translocation by the FocA anion channel
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1312
Abstract: The formate‐specific anion channel FocA of Escherichia coli belongs to the superfamily of homopentameric formate‐nitrite transporters (FNT). Minimally nine amino acid residues are conserved in the formate translocation pore of each protomer of the pentamer,… read more here.
Keywords: anion channel; translocation; formate; functional structural ... See more keywords