Mitochondrial protein translocation-associated degradation
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DOI: 10.1038/s41586-019-1227-y
Abstract: Mitochondrial biogenesis and functions depend on the import of precursor proteins via the ‘translocase of the outer membrane’ (TOM complex). Defects in protein import lead to an accumulation of mitochondrial precursor proteins that induces a… read more here.
Keywords: precursor proteins; associated degradation; translocation associated;
Overexpression of Translocation Associated Membrane Protein 2 Leading to Cancer-Associated Matrix Metalloproteinase Activation as a Putative Metastatic Factor for Human Oral Cancer
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DOI: 10.7150/jca.25666
Abstract: Translocation associated membrane protein 2 (TRAM2) has been characterized as a component of the translocon that is a gated channel at the endoplasmic reticulum (ER) membrane. TRAM2 is expressed in a wide variety of human… read more here.
Keywords: protein; associated membrane; cancer; membrane protein ... See more keywords