7-Hydorxyindirubin is capable of specifically inhibiting anticancer drug-induced YB-1 nuclear translocation without showing cytotoxicity in HepG2 hepatocellular carcinoma cells.
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DOI: 10.1016/j.bbrc.2021.01.048
Abstract: Hepatocellular carcinoma (HCC) is one of the most common human malignant tumors. It is known that in the cells of many cancers, including HCC, nuclear translocation and accumulation of YB-1 often indicates a poor prognosis.… read more here.
Keywords: translocation without; drug; induced nuclear; translocation ... See more keywords