Articles with "translocations constitute" as a keyword



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ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors.

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Published in 2021 at "Cancer discovery"

DOI: 10.1158/2159-8290.cd-20-1052

Abstract: ZFTA (C11orf95)-a gene of unknown function-partners with a variety of transcriptional co-activators in translocations that drive supratentorial ependymoma, a frequently lethal brain tumor. Understanding the function of ZFTA is key to developing therapies that inhibit… read more here.

Keywords: chromatin; zfta; translocations constitute; fusion proteins ... See more keywords