Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.09.007
Abstract: G-protein-coupled receptors (GPCRs), also known as seven transmembrane receptors (7TMRs), typically interact with two distinct signal-transducers, i.e., G proteins and β-arrestins (βarrs). Interestingly, there are some non-canonical 7TMRs that lack G protein coupling but interact… read more here.
Keywords: intrinsic bias; bias non; transmembrane receptors; seven transmembrane ... See more keywords
Cryo-electron Microscopic Analysis of Single-Pass Transmembrane Receptors.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.1c01035
Abstract: Single-pass transmembrane receptors (SPTMRs) represent a diverse group of integral membrane proteins that are involved in many essential cellular processes, including signal transduction, cell adhesion, and transmembrane transport of materials. Dysregulation of the SPTMRs is… read more here.
Keywords: pass transmembrane; single pass; transmembrane; transmembrane receptors ... See more keywords
Logistic Regression of Ligands of Chemotaxis Receptors Offers Clues about Their Recognition by Bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2017.00088
Abstract: Because of relative simplicity of signal transduction pathway, bacterial chemotaxis sensory systems have been expected to be applied to biosensor. Tar and Tsr receptors mediate chemotaxis of Escherichia coli and have been studied extensively as… read more here.
Keywords: tar; carboxyl groups; transmembrane receptors; recognition ... See more keywords