Enhanced transmucosal delivery of itraconazole by thiolated d‐&agr;‐tocopheryl poly(ethylene glycol) 1000 succinate micelles for the treatment of Candida albicans
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DOI: 10.1016/j.ejpb.2017.08.012
Abstract: ABSTRACT This study aimed to investigate the transmucosal delivery of itraconazole (ITZ) by thiolated d‐&agr;‐tocopheryl poly(ethylene glycol) 1000 succinate (TPGS‐Cys) micelles. TPGS‐Cys polymer was successfully synthesized by the simple coupling between carboxyl‐activated TPGS and Cys… read more here.
Keywords: transmucosal delivery; cys micelles; tpgs cys; tpgs tpgs ... See more keywords
Ethosomal gel for rectal transmucosal delivery of domperidone: design of experiment, in vitro, and in vivo evaluation
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DOI: 10.1080/10717544.2022.2072542
Abstract: Abstract Despite high efficiency of domperidone (DOM) in prophylaxis of emesis accompanied with radiotherapy and chemotherapy, it still can bother cancer patients by its powerful side effects and difficulty of its oral administration. The study… read more here.
Keywords: transmucosal delivery; ethosomal gel; gel; rectal transmucosal ... See more keywords
Transmucosal delivery of melatonin-encapsulated niosomes in a mucoadhesive gel.
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DOI: 10.4155/tde-2018-0001
Abstract: AIM A transmucosal niosome gel was developed to improve the pharmacokinetics of exogenous melatonin. MATERIALS & METHODS The melatonin niosomes (MN) gel was characterized and melatonin levels were determined in healthy volunteers. RESULTS Micron-sized MN in… read more here.
Keywords: gel; transmucosal delivery; delivery melatonin; transmucosal ... See more keywords