A case for the reuse and adaptation of mechanistic computational models to study transplant immunology
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DOI: 10.1111/ajt.15623
Abstract: Computational mechanistic models constitute powerful tools for summarizing our knowledge in quantitative terms, providing mechanistic understanding, and generating new hypotheses. The present review emphasizes the advantages of reusing publicly available computational models as a way… read more here.
Keywords: transplant immunology; case reuse; reuse adaptation; computational models ... See more keywords
Transplant Immunology: Basic Immunology and Clinical Practice
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DOI: 10.2310/surg.2210
Abstract: Engraftment of a transplanted organ into an allogeneic host triggers a cascade of immunologic responses in the host that are designed to facilitate graft rejection. Modern donor-to-host matching techniques and immunosuppression protocols have successfully tempered… read more here.
Keywords: clinical practice; transplant immunology; graft; rejection ... See more keywords
Intestinal Transplant Immunology and Intestinal Graft Rejection: From Basic Mechanisms to Potential Biomarkers
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DOI: 10.3390/ijms24054541
Abstract: Intestinal transplantation (ITx) remains a lifesaving option for patients suffering from irreversible intestinal failure and complications from total parenteral nutrition. Since its inception, it became obvious that intestinal grafts are highly immunogenic, due to their… read more here.
Keywords: graft rejection; transplant immunology; intestinal transplant; immunology intestinal ... See more keywords