Effective suppression of donor specific antibody production by Cathepsin S inhibitors in a mouse transplantation model
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.09.007
Abstract: Abstract Donor‐specific antibodies (DSA) are a major risk factor for antibody‐mediated rejection (ABMR) in solid organ transplantation, and ABMR remains a medical challenge. Therefore, effective anti‐ABMR therapies are needed to improve overall graft survival. Cathepsin… read more here.
Keywords: production; antibody; transplantation; cat ... See more keywords
Rapamycin treated tol-dendritic cells derived from BM-MSCs reversed graft rejection in a rat liver transplantation model by inducing CD8+CD45RC-Treg.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.03.018
Abstract: OBJECTIVE To investigate the influence of tolerance dendritic cells (tolDCs), generated from Bone marrow mesenchymal stem cells (BM-MSCs) treated with rapamycin (Rapa) on liver allograft survival in a rat acute liver transplantation model. METHODS Different… read more here.
Keywords: cd8; liver transplantation; transplantation; cd45rc ... See more keywords
The utility of early post-liver transplantation model for end-stage liver disease score in prediction of long-term mortality
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Gastroenterology"
DOI: 10.20524/aog.2019.0420
Abstract: Background: Little is known about the prognostic ability of post-liver transplantation (LT) model for end-stage liver disease (MELD) score measurement in assessing long-term outcomes. The aim of the present study was to investigate this possible… read more here.
Keywords: transplantation model; mortality; liver transplantation; post liver ... See more keywords