Expansion of transplanted islets in mice by co-transplantation with adipose tissue-derived mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Heliyon"
DOI: 10.1016/j.heliyon.2018.e00632
Abstract: The shortage of donor islets is a significant obstacle for widespread clinical application of pancreatic islet transplantation. To investigate whether adipose tissue-derived mesenchymal stem cells (ADSCs) induce expansion of transplanted islets, we performed co-transplantation experiments… read more here.
Keywords: transplanted islets; derived mesenchymal; transplantation; mesenchymal stem ... See more keywords
Quantitative and longitudinal imaging of intramuscular transplanted islets of Langerhans with SPECT using [ 123I]IBZM
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DOI: 10.1111/dom.12857
Abstract: A non‐invasive imaging method to monitor islet grafts could provide novel and improved insight into the fate of transplanted islets and, potentially, monitor the effect of therapeutic interventions. Therefore, such an imaging method could help… read more here.
Keywords: transplanted islets; 123i ibzm; longitudinal graft; graft ... See more keywords
Skeletal Myoblast Cells Enhance the Function of Transplanted Islets in Diabetic Mice
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DOI: 10.1155/2024/5574968
Abstract: Islet transplantation (ITx) is an established and safe alternative to pancreas transplantation for type 1 diabetes mellitus (T1DM) patients. However, most ITx recipients lose insulin independence by 3 years after ITx due to early graft… read more here.
Keywords: transplanted islets; myoblast; skeletal myoblast; function ... See more keywords
Enhancing the functional output of transplanted islets in diabetic mice using a drug-eluting scaffold
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DOI: 10.1186/s13036-018-0098-3
Abstract: BackgroundIslet transplantation is increasingly used in the diabetic patients to control the blood glucose level. However, the functional output of transplanted islets remains hampered due to the local inflammation, loss of islets, etc. To that… read more here.
Keywords: functional output; transplanted islets; drug eluting; output transplanted ... See more keywords
The Influence of Microenvironment on Survival of Intraportal Transplanted Islets
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DOI: 10.3389/fimmu.2022.849580
Abstract: Clinical islet transplantation has the potential to cure type 1 diabetes. Despite recent therapeutic success, it is still uncommon because transplanted islets are damaged by multiple challenges, including instant blood mediated inflammatory reaction (IBMIR), inflammatory… read more here.
Keywords: influence microenvironment; microenvironment survival; transplanted islets; transplantation ... See more keywords