Divergent evolutionary trajectories in transplanted tumor models
Sign Up to like & getrecommendations! Published in 2017 at "Nature Genetics"
DOI: 10.1038/ng.3983
Abstract: Human-derived tumor models are becoming popular in the context of personalized medicine, but a new study shows that these models could be less representative of primary tumors than previously thought, particularly when using late passages. read more here.
Keywords: trajectories transplanted; tumor models; evolutionary trajectories; transplanted tumor ... See more keywords
Tim3scFv-Transforming Lactobacillus Inhibits Transplanted Tumor of Renal-Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Urologia Internationalis"
DOI: 10.1159/000525956
Abstract: Introduction: T-cell immunoglobulin-3 (Tim-3) antibody drugs can treat malignant renal tumors but are expensive. To overcome this limitation, Lactococcus lactis host bacteria were used to express Tim-3 single-chain antibodies. Methods: The pLAN-CTB-Tim3scFv plasmid was constructed… read more here.
Keywords: ctb tim3scfv; renal cell; tim3scfv; transplanted tumor ... See more keywords