An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2021.05.005
Abstract: Oral administration is the most commonly used route for drug delivery owing to its cost-effectiveness, ease of administration, and high patient compliance. However, the absorption of orally delivered compounds is a complex process that greatly… read more here.
Keywords: vitro vivo; studying transport; vivo; transport drugs ... See more keywords
Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR.
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DOI: 10.1016/j.resmic.2017.01.005
Abstract: Proton-dependent oligopeptide transporters (POTs) are secondary active transporters found in all kingdoms of life. POTs utilize the proton electrochemical gradient for the uptake of nutrient dipeptides and tripeptides. The human POT hPepT1 is known to… read more here.
Keywords: escherichia coli; transport drugs; proton; several hpept1 ... See more keywords