Unraveling the thermodynamics, enzyme activity and denaturation studies of Triprolidine hydrochloride binding with model transport protein
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.116569
Abstract: Abstract The binding mechanism and stability study of triprolidine hydrochloride (TRP), a H1-receptor antagonist with model transport protein, bovine serum albumin (BSA) has been investigated using isothermal titration calorimetry (ITC), enzyme kinetics, chemical and thermal… read more here.
Keywords: triprolidine hydrochloride; activity; transport protein; model transport ... See more keywords
Hypoxia-Inducible Factor-2alpha Affects the MEK/ERK Signaling Pathway via Primary Cilia in Connection with the Intraflagellar Transport Protein 88 Homolog
Sign Up to like & getrecommendations! Published in 2023 at "Molecular and Cellular Biology"
DOI: 10.1080/10985549.2023.2198931
Abstract: Abstract The ability of cells to communicate with their surrounding is a prerequisite for essential processes such as proliferation, apoptosis, migration, and differentiation. To this purpose, primary cilia serve as antennae-like structures on the surface… read more here.
Keywords: transport protein; intraflagellar transport; hypoxia; factor ... See more keywords
Lipid transport protein ORP2A promotes glucose signaling by facilitating RGS1 degradation.
Sign Up to like & getrecommendations! Published in 2023 at "Plant physiology"
DOI: 10.1093/plphys/kiad238
Abstract: Heterotrimeric GTP-binding proteins (G proteins) are a group of regulators essential for signal transmission into cells. Regulator of G-protein signaling 1 (AtRGS1) possesses intrinsic GTPase-accelerating protein (GAP) activity and could suppress G-protein and glucose signal… read more here.
Keywords: signaling facilitating; transport protein; protein orp2a; degradation ... See more keywords
Two Cases of Thyrotoxicosis and Euglycemic Diabetic Ketoacidosis Under Sodium-glucose Transport Protein 2 Inhibitor Treatment
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DOI: 10.2169/internalmedicine.8830-21
Abstract: Thyrotoxicosis and sodium-glucose transport protein 2 inhibitors (SGLT2is) are associated with the induction of euglycemic diabetic ketoacidosis (euDKA). We herein report two cases of euDKA in patients with diabetes mellitus wherein both thyrotoxicosis and SGLT2i… read more here.
Keywords: transport protein; glucose transport; euglycemic diabetic; diabetic ketoacidosis ... See more keywords
Natural Ligand-Mimetic and Nonmimetic Inhibitors of the Ceramide Transport Protein CERT
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042098
Abstract: Lipid transfer proteins (LTPs) are recognized as key players in the inter-organelle trafficking of lipids and are rapidly gaining attention as a novel molecular target for medicinal products. In mammalian cells, ceramide is newly synthesized… read more here.
Keywords: transport protein; natural ligand; transport; protein cert ... See more keywords