Articles with "transporter complex" as a keyword



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Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

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Published in 2018 at "eLife"

DOI: 10.7554/elife.36620

Abstract: Nitrogen-containing-bisphosphonates (N-BPs) are a class of drugs widely prescribed to treat osteoporosis and other bone-related diseases. Although previous studies have established that N-BPs function by inhibiting the mevalonate pathway in osteoclasts, the mechanism by which… read more here.

Keywords: transporter complex; identification transporter; containing bisphosphonates; nitrogen containing ... See more keywords