Comparative genomic analysis of ABC transporter genes in Tenebrio molitor and four other tenebrionid beetles (Coleoptera: Tenebrionidea).
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21916
Abstract: ATP-binding cassette (ABC) transporters, one of the largest transmembrane protein families, transport a diverse number of substate across membranes. Details of their diverse physiological functions have not been established. Here, we identified 87 ABC transporter… read more here.
Keywords: tenebrio molitor; abc transporter; transporter genes;
Concomitant knockout of target and transporter genes in filamentous fungi by genome co‐editing
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DOI: 10.1002/mbo3.1280
Abstract: In most countries, genetically modified microorganisms are not approved for use for fermentation in the food industry. Therefore, random mutagenesis and subsequent screening are performed to improve the productivities of valuable metabolites and enzymes as… read more here.
Keywords: genome editing; genetically modified; strain; transporter genes ... See more keywords
Annotation and characterization of Cd-responsive metal transporter genes in rapeseed (Brassica napus)
Sign Up to like & getrecommendations! Published in 2017 at "BioMetals"
DOI: 10.1007/s10534-017-0072-4
Abstract: In higher plants, heavy metal transporters are responsible for metal uptake, translocation and homeostasis. These metals include essential metals such as zinc (Zn) or manganese (Mn) and non-essential metals like cadmium (Cd) or lead (Pb).… read more here.
Keywords: transporter genes; metal; brassica napus; rapeseed brassica ... See more keywords
Transporter genes ABCG2 rs2231142 and ABCB1 rs1128503 polymorphisms and atorvastatin response in Chilean subjects
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.12607
Abstract: Statins are first‐line therapy for reducing high cholesterol levels. However, response to these drugs shows high interindividual variability. We aimed to investigate the influence of two single nucleotide polymorphisms (SNP) (ABCB1 rs1128503 and ABCG2 rs2231142)… read more here.
Keywords: abcg2 rs2231142; response; abcb1 rs1128503; transporter genes ... See more keywords
Architecture of polymorphisms in the human genome reveals functionally important and positively selected variants in immune response and drug transporter genes
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DOI: 10.1186/s40246-018-0175-1
Abstract: BackgroundGenetic polymorphisms can contribute to phenotypic differences amongst individuals, including disease risk and drug response. Characterization of genetic polymorphisms that modulate gene expression and/or protein function may facilitate the identification of the causal variants. Here,… read more here.
Keywords: polymorphisms human; response; human genome; transporter genes ... See more keywords
In vivo recombination of Saccharomyces eubayanus maltose-transporter genes yields a chimeric transporter that enables maltotriose fermentation
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007853
Abstract: Saccharomyces eubayanus is the non-S. cerevisiae parent of the lager-brewing hybrid S. pastorianus. In contrast to most S. cerevisiae and Frohberg-type S. pastorianus strains, S. eubayanus cannot utilize the α-tri-glucoside maltotriose, a major carbohydrate in… read more here.
Keywords: maltotriose fermentation; pastorianus; transporter genes; gene ... See more keywords
Associations Between Genetic Polymorphisms Within Transporter Genes and Clinical Response to Methotrexate in Chinese Rheumatoid Arthritis Patients: A Pilot Study
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DOI: 10.2147/pgpm.s350417
Abstract: Purpose To investigate the associations between genetic polymorphisms within transporter genes and clinical response to methotrexate (MTX) in Chinese rheumatoid arthritis (RA) patients. Patients and Methods A total of 100 RA patients receiving MTX were… read more here.
Keywords: das28 esr; transporter genes; response; genetic polymorphisms ... See more keywords
Effect of 5-fluorouracil on mRNA expression of drug metabolizing enzyme and transporter genes in human hepatoma cell lines.
Sign Up to like & getrecommendations! Published in 2021 at "Biomedical research"
DOI: 10.2220/biomedres.42.121
Abstract: Fluoropyrimidines such as 5-fluorouracil (5-FU) are well known to have drug-drug interactions with anticoagulant medications such as warfarin. This study investigated the mRNA expression of pharmacokinetic (PK)-related genes in response to 5-FU using the hepatocarcinoma… read more here.
Keywords: cell lines; transporter genes; drug; expression ... See more keywords
Effect of early neonatal development and delayed feeding post‐hatch on jejunal and ileal calcium and phosphorus transporter genes expression in broiler chickens1
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DOI: 10.3382/ps/pey546
Abstract: ABSTRACT Calcium (Ca) and phosphorus (P) are essential minerals involved in many biological processes including bone development and mineralization. Plasma concentration of both minerals is tightly regulated, and Ca and P homeostasis is maintained via… read more here.
Keywords: broiler; transporter genes; expression; calcium phosphorus ... See more keywords
Identification of sugar transporter genes and their roles in the pathogenicity of Verticillium dahliae on cotton
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1123523
Abstract: Introduction Verticillium wilt (VW) caused by Verticillium dahliae is a soil-borne vascular fungal disease that severely affects cotton yield and fiber quality. Sugar metabolism plays an important role in the growth and pathogenicity of V.… read more here.
Keywords: dahliae; transporter genes; pathogenicity; sugar transporter ... See more keywords
ATP-Binding Cassette (ABC) Transporter Genes Involved in Pyrethroid Resistance in the Malaria Vector Anopheles sinensis: Genome-Wide Identification, Characteristics, Phylogenetics, and Expression Profile
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DOI: 10.3390/ijms20061409
Abstract: background: The ATP-binding cassette (ABC) transporters family is one of the largest families of membrane proteins existing in all living organisms. Pyrethroid resistance has become the largest unique obstacle for mosquito control worldwide. ABC transporters… read more here.
Keywords: abc transporter; transporter genes; pyrethroid resistance; abc ... See more keywords