Molecular characteristics supporting l-Type amino acid transporter 1 (LAT1)-mediated translocation.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104921
Abstract: l-Type amino acid transporter 1 (LAT1) is an interesting protein due to its peculiar expression profile. It can be utilized not only as a carrier for improved or targeted drug delivery, e.g., into the brain… read more here.
Keywords: amino acid; transporter lat1; type amino; acid transporter ... See more keywords
Structural properties for selective and efficient l‐type amino acid transporter 1 (LAT1) mediated cellular uptake
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DOI: 10.1016/j.ijpharm.2018.04.025
Abstract: Graphical abstract Figure. No Caption available. Abstract l‐Type amino acid transporter 1 (LAT1) is a sodium‐independent exchanger transporting large neural amino acids and several amino‐acid mimicking drugs across the cell membranes. LAT1 is highly expressed… read more here.
Keywords: amino acid; transporter lat1; type amino; acid transporter ... See more keywords
The Nutraceutical Alliin From Garlic Is a Novel Substrate of the Essential Amino Acid Transporter LAT1 (SLC7A5)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.877576
Abstract: The plasma membrane transporter LAT1 (SLC7A5) is a crucial player for cell homeostasis because it is responsible for providing cells with essential amino acids and hormones. LAT1 forms a functional heterodimer with the cell surface… read more here.
Keywords: lat1 slc7a5; alliin; essential amino; lat1 ... See more keywords