A two–tiered system for selective receptor and transporter protein degradation
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010446
Abstract: Diverse physiology relies on receptor and transporter protein down–regulation and degradation mediated by ESCRTs. Loss–of–function mutations in human ESCRT genes linked to cancers and neurological disorders are thought to block this process. However, when homologous… read more here.
Keywords: transporter protein; transporter; two tiered; receptor transporter ... See more keywords
Identification of potential candidate vaccines against Mycobacterium ulcerans based on the major facilitator superfamily transporter protein
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1023558
Abstract: Buruli ulcer is a neglected tropical disease that is characterized by non-fatal lesion development. The causative agent is Mycobacterium ulcerans (M. ulcerans). There are no known vectors or transmission methods, preventing the development of control… read more here.
Keywords: superfamily transporter; transporter protein; facilitator superfamily; mycobacterium ulcerans ... See more keywords
Advances in sodium-glucose transporter protein 2 inhibitors and tumors
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DOI: 10.3389/fonc.2025.1522059
Abstract: Tumor is a major challenge to global health and has received extensive attention worldwide due to its high degree of malignancy and poor prognosis. Although the clinical application of targeted therapy and immunotherapy has improved… read more here.
Keywords: glucose transporter; advances sodium; transporter protein; sodium glucose ... See more keywords