SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARĪ³
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DOI: 10.1016/j.celrep.2021.109190
Abstract: SUMMARY Pathological lipid accumulation is often associated with enhanced uptake of free fatty acids via specific transporters in cardiomyocytes. Here, we identify SIRT6 as a critical transcriptional regulator of fatty acid transporters in cardiomyocytes. We… read more here.
Keywords: acid transporters; lipid accumulation; fatty acid; transporters cardiomyocytes ... See more keywords