Articles with "transposable element" as a keyword



State‐of‐the‐art in transposable element modulation affected by drugs in malignant prostatic cancer cells

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Published in 2024 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.30557

Abstract: Over recent years, the investigation of transposable elements (TEs) has granted researchers a deeper comprehension of their characteristics and functions, particularly regarding their significance in the mechanisms contributing to cancer development. This manuscript focuses on… read more here.

Keywords: cancer; art transposable; modulation affected; state art ... See more keywords
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Disrupting the disruptors: the consequences of mutations in mobile elements for ecologically important life history traits

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Published in 2020 at "Evolutionary Ecology"

DOI: 10.1007/s10682-020-10038-0

Abstract: Transposable elements are a nearly ubiquitous component of eukaryotic genomes. While often described as parasitic genetic elements, other evidence suggests that transposable elements can become domesticated and contribute to organismal function. There is little empirical… read more here.

Keywords: life history; transposable elements; transposable element; ecology ... See more keywords

Transposable element dysregulation in systemic lupus erythematosus and regulation by histone conformation and Hsp90.

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Published in 2018 at "Clinical immunology"

DOI: 10.1016/j.clim.2018.08.011

Abstract: Systemic lupus erythematosus (SLE) represents an autoimmune disease in which activation of the type I interferon pathway leads to dysregulation of tolerance and the generation of autoantibodies directed against nuclear constituents. The mechanisms driving the… read more here.

Keywords: transposable element; systemic lupus; dysregulation; expression ... See more keywords

Stress affects the epigenetic marks added by natural transposable element insertions in Drosophila melanogaster

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-30491-w

Abstract: Transposable elements are emerging as an important source of cis-acting regulatory sequences and epigenetic marks that could influence gene expression. However, few studies have dissected the role of specific transposable element insertions on epigenetic gene… read more here.

Keywords: epigenetic marks; transposable element; bari jheh; element insertions ... See more keywords

DNA gains and losses in gigantic genomes do not track differences in transposable element-host silencing interactions

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Published in 2025 at "Communications Biology"

DOI: 10.1038/s42003-025-08127-3

Abstract: Size evolution among gigantic genomes involves gain and loss of many gigabases of transposable elements (TEs), sequences that parasitize host genomes. Vertebrates suppress TEs using piRNA and KRAB-ZFP pathways. TEs and hosts coevolve in an… read more here.

Keywords: host; host silencing; gigantic genomes; transposable element ... See more keywords

DNA methylation dynamics at transposable elements in mammals.

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Published in 2019 at "Essays in biochemistry"

DOI: 10.1042/ebc20190039

Abstract: Transposable elements dominate the mammalian genome, but their contribution to genetic and epigenetic regulation has been largely overlooked. This was in part due to technical limitations, which made the study of repetitive sequences at single… read more here.

Keywords: methylation; transposable element; methylation dynamics; transposable elements ... See more keywords

Tracking the genome-wide outcomes of a transposable element burst over decades of amplification

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Published in 2017 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1716459114

Abstract: Significance Rice (Oryza sativa) has a unique combination of attributes that made it an ideal host to track the natural behavior of very active transposable elements (TEs) over generations. In this study, we have exploited… read more here.

Keywords: transposable element; burst decades; burst; host ... See more keywords

piRNA Clusters Need a Minimum Size to Control Transposable Element Invasions

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Published in 2020 at "Genome Biology and Evolution"

DOI: 10.1093/gbe/evaa064

Abstract: Abstract piRNA clusters are thought to repress transposable element (TE) activity in mammals and invertebrates. Here, we show that a simple population genetics model reveals a constraint on the size of piRNA clusters: The total… read more here.

Keywords: minimum size; pirna; transposable element; pirna clusters ... See more keywords

Insertion of a mMoshan transposable element in PpLMI1, is associated with the absence or globose phenotype of extrafloral nectaries in peach [Prunus persica (L.) Batsch].

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Published in 2022 at "Horticulture research"

DOI: 10.1093/hr/uhab044

Abstract: Most commercial peach [Prunus persica (L.) Batsch] cultivars have leaves with extrafloral nectaries (EFNs). Breeders have selected this character over time, as they observed that the eglandular phenotype resulted in high susceptibility to peach powdery… read more here.

Keywords: prunus persica; transposable element; peach; persica batsch ... See more keywords

Dynamics and Impacts of Transposable Element Proliferation in the Drosophila nasuta Species Group Radiation

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Published in 2022 at "Molecular Biology and Evolution"

DOI: 10.1093/molbev/msac080

Abstract: Abstract Transposable element (TE) mobilization is a constant threat to genome integrity. Eukaryotic organisms have evolved robust defensive mechanisms to suppress their activity, yet TEs can escape suppression and proliferate, creating strong selective pressure for… read more here.

Keywords: transposable element; proliferation; species group; nasuta species ... See more keywords

Whole genome duplication and transposable element proliferation drive genome expansion in Corydoradinae catfishes

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Published in 2018 at "Proceedings of the Royal Society B: Biological Sciences"

DOI: 10.1098/rspb.2017.2732

Abstract: Genome size varies significantly across eukaryotic taxa and the largest changes are typically driven by macro-mutations such as whole genome duplications (WGDs) and proliferation of repetitive elements. These two processes may affect the evolutionary potential… read more here.

Keywords: transposable element; whole genome; size; hpd ... See more keywords