A Mos1 transposase in vivo assay to screen new HIV-1 integrase inhibitors
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DOI: 10.1007/s10709-018-0007-1
Abstract: The integrase and transposase enzymes of retrovirus and transposons, respectively, share the catalytic DDE domain. In vitro assays showed that inhibitors of HIV-1 integrase generally inhibit the mariner Mos1 transposase. Using a Drosophila strain in… read more here.
Keywords: integrase; mos1 transposase; transposase vivo; transposase ... See more keywords