Transposon insertional mutagenesis of diverse yeast strains suggests coordinated gene essentiality polymorphisms.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29228-1
Abstract: Due to epistasis, the same mutation can have drastically different phenotypic consequences in different individuals. This phenomenon is pertinent to precision medicine as well as antimicrobial drug development, but its general characteristics are largely unknown.… read more here.
Keywords: insertional mutagenesis; essentiality; transposon insertional; gene essentiality ... See more keywords