piRNA-independent transposon silencing by the Drosophila THO complex.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.08.021
Abstract: piRNAs guide Piwi/Panoramix-dependent H3K9me3 chromatin modification and transposon silencing during Drosophila germline development. The THO RNA export complex is composed of Hpr1, Tho2, and Thoc5-7. Null thoc7 mutations, which displace Thoc5 and Thoc6 from a… read more here.
Keywords: independent transposon; transposon silencing; pirna independent; transposon ... See more keywords
Induction of transposon silencing in the Drosophila germline
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry (Moscow)"
DOI: 10.1134/s0006297917050042
Abstract: In this review we consider the role of the piRNA system in transposable element silencing in the Drosophila melanogaster germline. We focus on new data that demonstrate the mechanisms of initiation of piRNA biogenesis in… read more here.
Keywords: silencing drosophila; drosophila germline; transposon silencing; induction transposon ... See more keywords
DNA methyltransferase CHROMOMETHYLASE3 prevents ONSEN transposon silencing under heat stress
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DOI: 10.1371/journal.pgen.1009710
Abstract: DNA methylation plays crucial roles in transposon silencing and genome integrity. CHROMOMETHYLASE3 (CMT3) is a plant-specific DNA methyltransferase responsible for catalyzing DNA methylation at the CHG (H = A, T, C) context. Here, we identified… read more here.
Keywords: methylation; heat stress; transposon silencing; cmt3 ... See more keywords
Essential roles of Windei and nuclear monoubiquitination of Eggless/SETDB1 in transposon silencing
Sign Up to like & getrecommendations! Published in 2019 at "EMBO reports"
DOI: 10.15252/embr.201948296
Abstract: Eggless/SETDB1 (Egg), the only essential histone methyltransferase (HMT) in Drosophila, plays a role in gene repression, including piRNA‐mediated transposon silencing in the ovaries. Previous studies suggested that Egg is post‐translationally modified and showed that Windei… read more here.
Keywords: monoubiquitination; transposon silencing; egg; eggless setdb1 ... See more keywords