Effect of ablative laser on in vitro transungual delivery
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DOI: 10.1016/j.ijpharm.2017.09.048
Abstract: ABSTRACT Topical therapy of nail psoriasis using methotrexate has not been realized due to the high molecular weight and low permeability of the compound. In this study, we used a 2940 nm fractional ablative laser… read more here.
Keywords: ablative laser; laser; microscopy; delivery ... See more keywords
Fabrication of Dissolvable Microneedle Patches Using an Innovative Laser-Cut Mould Design to Shortlist Potentially Transungual Delivery Systems: In Vitro Evaluation
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DOI: 10.1208/s12249-019-1429-5
Abstract: There has been a great interest towards transungual delivery systems due to limited drug penetration for the treatment of nail diseases. More important, antifungal oral medicaments used may cause serious side effects including liver damage.… read more here.
Keywords: laser; delivery systems; dissolvable microneedle; drug ... See more keywords
Design, Development, and Evaluation of Constant Voltage Iontophoresis for the Transungual Delivery of Efinaconazole
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DOI: 10.3390/pharmaceutics15051422
Abstract: The efficacy of topical antifungal therapy in onychomycosis has been hindered by the failure of the antimycotic to permeate the nail plate. This research aims to design and develop a transungual system for the effective… read more here.
Keywords: transungual delivery; voltage; delivery efinaconazole; design ... See more keywords