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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222111586
Abstract: Hypoxia is known to impair mitochondrial and endoplasmic reticulum (ER) homeostasis. Post-hypoxic perturbations of the ER proteostasis result in the accumulation of misfolded/unfolded proteins leading to the activation of the Unfolded Protein Response (UPR). Mitochondrial…
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Keywords:
post hypoxic;
trap1 deficient;
activation;